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KMID : 1098420080160010009
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Korean Journal of Medicinal Crop Science
2008 Volume.16 No. 1 p.9 ~ p.15
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Enhancement of Immune-Potentiation of Cichorium endivia L. by Ultrasonification Extraction Process
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Kwon Min-Cheol
Lee Hyeon-Yong
Ahn Ju-Hee
Qadir Syed Abdul
Han Jae-Gun
Lee Dal-Ho
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Abstract
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Immune-potentiation of Chicorium endivia L. were investigated on follows extracts associated with ultrasonification process at 60 kHz and showed the highest promotion of human B and T cell growth, about compared to the control. The secretion of TNF- and IL-6 was also enhanced by the addition of the extracts. NK cell activation was Improved up to 1.37 times higher than the control, through adding extracts. It was also found that extracts from C. endivia L. could yield higher nitric oxide production from macrophage than Lipopolysaccaharides (LPS). It can be concluded that, in general, the extracts treated with ultrasonification has higher immune activity than others, possibly by higher yielding immune-modulatory activity than conventional extraction process. The optimum condition for the extraction of C. endivia L. is ethanol extraction at associated with ultrasonification.
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KEYWORD
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Chicorium endivia L., Immune-Potentiation, Ultrasonification
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